CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Analysis of CD8+ T cell-mediated inhibition of hepatitis C virus replication using a novel immunological model
DOI 10.1055/s-0029-1191937
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Autor:innenJ Jo, U Aichele, N Kersting, R Klein, P Aichele, E Bisse, AK Sewell, HE Blum, R Bartenschlager, V Lohmann, R Thimme
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
While virus-specific CD8+ T cells are required for the control of hepatitis C virus (HCV) infection, the extent to which different effector functions contribute to the inhibition of viral replication has not been well defined. To address this important issue, we developed a novel immunological model by stably transducing the HLA-A2 gene into the replicon system, matching the epitope sequence of the replicon to the s…
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Zitierempfehlung
J Jo, U Aichele, N Kersting, R Klein, P Aichele, E Bisse, AK Sewell, HE Blum, R Bartenschlager, V Lohmann, R Thimme (2009) Analysis of CD8+ T cell-mediated inhibition of hepatitis C virus replication using a novel immunological model. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191937
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