CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Immunogenic maturation of liver-resident endothelial cells promotes CD8 effector cell differentiation in the absence of co-stimulation
DOI 10.1055/s-0029-1191938
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Nachweis in CareLit
Autor:innenMA Kern, A Popov, A Limmer, L Diehl, J Schultze, PA Knolle
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Generation of CD8+ T cell immunity depends on costimulatory signals delivered by fully mature antigen-presenting dendritic cells (DCs), which are activated by pathogen-associated molecular patterns (PAMPs) through pattern-recognition receptors (PRR). In contrast, immature DCs contribute to T cell tolerance by delivery of coinhibitory signals. Liver sinusoidal endothelial cells (LSEC) are unique organ-resident antige…
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Zitierempfehlung
MA Kern, A Popov, A Limmer, L Diehl, J Schultze, PA Knolle (2009) Immunogenic maturation of liver-resident endothelial cells promotes CD8 effector cell differentiation in the absence of co-stimulation. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191938
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