CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Lower hepatitis B virus productivity in HBeAg negative patients is not due to accumulation of mutations within viral DNA regulatory regions
DOI 10.1055/s-0029-1191940
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Autor:innenA Köpke, T Volz, M Lütgehetmann, AW Lohse, J Petersen, M Dandri
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Understanding of factors regulating activity of the covalently closed circular DNA (cccDNA), the template of hepatitis B virus (HBV) transcription, is important to elucidate viral persistence mechanisms. Quantitative measurement of HBV DNA and cccDNA loads in human liver biopsies revealed that HBV replication pathway was significantly reduced in most treatment naïve HBeAg-negative individuals and impairment of virio…
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Zitierempfehlung
A Köpke, T Volz, M Lütgehetmann, AW Lohse, J Petersen, M Dandri (2009) Lower hepatitis B virus productivity in HBeAg negative patients is not due to accumulation of mutations within viral DNA regulatory regions. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191940
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