CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Assessment of the Relevance of a CD14 Gene Polymorphism on RNA Polymerase II DNA Binding by Haplotype-Specific Immunoprecipitation (HaploChIP)
DOI 10.1055/s-0029-1191944
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Autor:innenJ Mertens, R Bregadze, E Askar, G Ramadori, S Mihm
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aim: Genetic background may influence susceptibility and progression of various diseases. A polymorphic site within the CD14 gene, rs2569190 / C-159T, was described to be associated with soluble CD14 levels (sCD14) in hepatitis C virus (HCV) infected patients. Both, sCD14 and the membrane-associated form of CD14 (mCD14) are important compounds in mediating endotoxin sensing on myeloid and non-myeloid cells. In vitro…
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Zitierempfehlung
J Mertens, R Bregadze, E Askar, G Ramadori, S Mihm (2009) Assessment of the Relevance of a CD14 Gene Polymorphism on RNA Polymerase II DNA Binding by Haplotype-Specific Immunoprecipitation (HaploChIP). Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191944
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