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The chemokine receptor CXCR3 mediates NK cell recruitment and limits injury after toxic liver damage

M Moreno Zaldivar, M Berres, P Schmitz, C Offermanns, KR Karlmark, F Tacke, N Gassler, C Trautwein, HE Wasmuth · Zeitschrift für Gastroenterologie · Ausgabe 01/2009

DOI 10.1055/s-0029-1191946

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Autor:innenM Moreno Zaldivar, M Berres, P Schmitz, C Offermanns, KR Karlmark, F Tacke, N Gassler, C Trautwein, HE Wasmuth
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Aims: Chemokines play an important role in liver injury by modulation of immune cell recruitment to the damaged liver. NK and NKT cells are known to be important contributers to liver cell damage. Their recruitment is mediated by the CXCR3 ligands CXCL9 and CXCL10. But the role of CXCR3 has not yet been evaluated in acute liver injury. Material and Methods: Acute liver injury was induced by injection of CCl4 (0.7mg/…

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M Moreno Zaldivar, M Berres, P Schmitz, C Offermanns, KR Karlmark, F Tacke, N Gassler, C Trautwein, HE Wasmuth (2009) The chemokine receptor CXCR3 mediates NK cell recruitment and limits injury after toxic liver damage. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191946

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