CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Inhibition of antigen-specific CD8+ T cell proliferation using peptide pools- Possible mechanisms
DOI 10.1055/s-0029-1191956
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Autor:innenP Suneetha, V Schlaphoff, C Wang, KA Stegmann, P Fytili, SK Sarin, MP Manns, M Cornberg, H Wedemeyer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Studying T cell proliferation in response to peptide pool stimulation is an important readout in vaccine development and epitope discovery studies. We have shown that increased concentration as well as number of peptides per pool inhibits the proliferation of antigen-specific CD8 T cells (GASL, 2008). Understanding the possible mechanisms underlying this would help improving the methodological limitations of using p…
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Zitierempfehlung
P Suneetha, V Schlaphoff, C Wang, KA Stegmann, P Fytili, SK Sarin, MP Manns, M Cornberg, H Wedemeyer (2009) Inhibition of antigen-specific CD8+ T cell proliferation using peptide pools- Possible mechanisms. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191956
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