CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Spontaneous Chronic Liver Inflammation in a Transgenic Mouse Model of Autoimmune Hepatitis: Impact and Regulation of Autoreactive CD8+ T Cells
DOI 10.1055/s-0029-1191959
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Autor:innenM Zierden, E Kühnen, M Odenthal, HP Dienes
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2009
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease of unknown cause. Autoreactive T cells are believed to trigger the destruction of hepatocytes but the pathogenesis of AIH remains poorly understood. To investigate liver-specific CD8+ T-cell responses as well as the impact and regulation of autoreactive CD8+ T cells in the pathogenesis of AIH, we have generated transgenic mice that express the influe…
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Zitierempfehlung
M Zierden, E Kühnen, M Odenthal, HP Dienes (2009) Spontaneous Chronic Liver Inflammation in a Transgenic Mouse Model of Autoimmune Hepatitis: Impact and Regulation of Autoreactive CD8+ T Cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0029-1191959
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