CareLit · DOI-Nachweis · Pneumologie
Imbalanced expression of the type I TGF-beta receptors ALK-1 and ALK-5 in pulmonary fibrosis
DOI 10.1055/s-0029-1202436
Bibliografische Angaben
Nachweis in CareLit
Autor:innenI Chrobak, N Banthien, K Kitowska, M Königshoff, W Seeger, O Eickelberg
ZeitschriftPneumologie
Ausgabe02/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Einleitung: Idiopathic pulmonary fibrosis (IPF) is a devastating disease with no effective treatment options. The lungs of IPF patients are characterized by alveolar epithelial cell injury, an accumulation of activated (myo)fibroblasts, and excessive deposition of extracellular matrix, especially collagens. This is, to a great extend, due to enhanced TGF-beta activity. In this study, we hypothesized that IPF is char…
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Zitierempfehlung
I Chrobak, N Banthien, K Kitowska, M Königshoff, W Seeger, O Eickelberg (2009) Imbalanced expression of the type I TGF-beta receptors ALK-1 and ALK-5 in pulmonary fibrosis. Pneumologie (02). https://doi.org/10.1055/s-0029-1202436
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