CareLit · DOI-Nachweis · Pneumologie
Increased Expression of Ect2, a Guanine Nucleotide Exchange Factor for Rho GTPases, in Hyperplastic Alveolar Epithelial Cells in IPF
DOI 10.1055/s-0029-1202439
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Königshoff, S Becker, O Eickelberg
ZeitschriftPneumologie
Ausgabe02/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Rationale: Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease characterized by fibroblast activation and extracellular matrix (ECM) remodelling, leading to distorted lung architecture and function. During disease progression, repetitive alveolar epithelial injury and repair processes lead to enhanced fibroblast activation and ECM deposition, but molecular mechanisms thereof remain elusive. P…
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Zitierempfehlung
M Königshoff, S Becker, O Eickelberg (2009) Increased Expression of Ect2, a Guanine Nucleotide Exchange Factor for Rho GTPases, in Hyperplastic Alveolar Epithelial Cells in IPF. Pneumologie (02). https://doi.org/10.1055/s-0029-1202439
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