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Mechanisms of Heteroresistance to Isoniazid and Rifampin of M. tuberculosis in Tashkent, Uzbekistan

S Thiel, J van Ingen, L Turaev, G Uzakova, D van Soolingen, H Hoffmann · Pneumologie · Ausgabe 03/2009

DOI 10.1055/s-0029-1213940

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Autor:innenS Thiel, J van Ingen, L Turaev, G Uzakova, D van Soolingen, H Hoffmann
ZeitschriftPneumologie
Ausgabe03/2009
Jahrgang / SeitenNicht angegeben

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Heteroresistance of Mycobacterium tuberculosis is defined as the co-existence of organisms either susceptible or resistant to an anti-tuberculosis drug in one patient. Here, we analyzed the underlying mechanisms of heteroresistance to INH and RMP in 35 tuberculosis (TB) patients from Tashkent, Uzbekistan, using the Genotype MTBDR assay. The MTBDR assay is designed to detect wild-type and mutations of the 81-bp hotsp…

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S Thiel, J van Ingen, L Turaev, G Uzakova, D van Soolingen, H Hoffmann (2009) Mechanisms of Heteroresistance to Isoniazid and Rifampin of M. tuberculosis in Tashkent, Uzbekistan. Pneumologie (03). https://doi.org/10.1055/s-0029-1213940

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