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Inhibition of abl tyrosine kinase supports antimicrobial activity in human alveolar macrophages

H Bruns, S Stenger, F Stegelmann, JH Ficker, M Wagner · Pneumologie · Ausgabe 03/2009

DOI 10.1055/s-0029-1213981

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Autor:innenH Bruns, S Stenger, F Stegelmann, JH Ficker, M Wagner
ZeitschriftPneumologie
Ausgabe03/2009
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Objective: Inhibition of abl tyrosine kinase by Gleevec® has revolutionized the therapy of chronic myeloic leukemia. The therapeutic manipulation of this ubiquitously expressed enzyme requires careful evaluation of potential side effects. This study was designed to investigate the functional implication of Gleevec® on the interaction of Mycobacterium tuberculosis (M.Tb) and its natural host cell, the alveolar macrop…

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Zitierempfehlung

H Bruns, S Stenger, F Stegelmann, JH Ficker, M Wagner (2009) Inhibition of abl tyrosine kinase supports antimicrobial activity in human alveolar macrophages. Pneumologie (03). https://doi.org/10.1055/s-0029-1213981

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