CareLit · DOI-Nachweis · Pneumologie
Microarray analysis reveals NFIB as a potential target of the matricellular protein WISP1 in alveolar epithelial cells in idiopathic pulmonary fibrosis
DOI 10.1055/s-0029-1214116
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Autor:innenN Rensing, N Balsara, J Wilhelm, O Eickelberg, M Königshoff
ZeitschriftPneumologie
Ausgabe03/2009
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Rationale: Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease, characterized by loss of respiratory function. Alveolar epithelial cell (AEC) hyperplasia, distorted epithelial-mesenchymal crosstalk, and enhanced extracellular matrix deposition by (myo)fibroblasts are key features of IPF. Previously, we identified the matricellular protein WISP1 as a profibrotic regulator in hyperplastic AEC in IPF and potent…
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Zitierempfehlung
N Rensing, N Balsara, J Wilhelm, O Eickelberg, M Königshoff (2009) Microarray analysis reveals NFIB as a potential target of the matricellular protein WISP1 in alveolar epithelial cells in idiopathic pulmonary fibrosis. Pneumologie (03). https://doi.org/10.1055/s-0029-1214116
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