CareLit · DOI-Nachweis · Klinische Pädiatrie
How can calcium pyrophosphate crystals induce inflammation in hypophosphatasia or chronic inflammatory joint diseases?
DOI 10.1055/s-0029-1214354
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Autor:innenC Beck, M Stenzel, P Schneider, HJ Girschick
ZeitschriftKlinische Pädiatrie
Ausgabe03/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Hypophosphatasia (HP) is a rare inborn error of bone and mineral metabolism characterized by a genetic defect in the gene of the tissue non-specific alkaline phosphatase (TNSALP). Calcium pyrophosphate dihydrate (CPPD) crystals are known to accumulate as substrates of TNSALP in tissues and joints of patients with HP. In CPPD-induced arthritis these crystals are known to induce an inflammatory response. HP patients d…
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Zitierempfehlung
C Beck, M Stenzel, P Schneider, HJ Girschick (2009) How can calcium pyrophosphate crystals induce inflammation in hypophosphatasia or chronic inflammatory joint diseases?. Klinische Pädiatrie (03). https://doi.org/10.1055/s-0029-1214354
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