REM sleep behavior disorder (RBD) and neurodegeneration

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First described by Schenck and collaborators, criteria for RBD are now defined by the ASDA and include complex behaviors during REM sleep with a loss of skeletal muscle atonia. Mild up to harmful body movements are associated with dream mentation and nightmares and disrupt sleep continuity. Polysomnographic evaluation is needed to establish a final diagnosis. RBD most likely reflects dysfunction in the brainstem cir…

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