CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Triggering and amplification of insulin secretion by dimethyl α-ketoglutarate, a membrane permeable α-ketoglutarate analogue
DOI 10.1055/s-0029-1221799
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Willenborg, U Panten, I Rustenbeck
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: It is estimated that about 70 percent of the insulin secretion stimulated by glucose and other fuels are due to the KATP channel-independent amplifying pathway which transduces signals from the energy metabolism to the exocytotic machinery of the beta-cell. Recently, cytosolic α-ketoglutarate has been suggested as a potential signalling compound in this context. This hypothesis was mainly based on the…
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Zitierempfehlung
M Willenborg, U Panten, I Rustenbeck (2009) Triggering and amplification of insulin secretion by dimethyl α-ketoglutarate, a membrane permeable α-ketoglutarate analogue. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0029-1221799
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