CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
PDX1 is involved in KLF11-induced inhibition of the human insulin promoter in rodent beta-cells
DOI 10.1055/s-0029-1221872
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Autor:innenG Päth, D Danassi, N Perakakis, W Zhou, M Alt, S van Loosen, K Laubner, J Seufert
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
KLF11 is a pancreas enriched member of the Sp1/KLF transcription factor family which plays an important role in mammalian gene regulation. Previously we demonstrated that human (h)KLF11) inhibits human insulin promoter (hInsP) activity in rodent beta-cell lines via an unknown mechanism. Here we present results from ongoing experiments in which we test the hypothesis that KLF11 interferes with the major hInsP transac…
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Zitierempfehlung
G Päth, D Danassi, N Perakakis, W Zhou, M Alt, S van Loosen, K Laubner, J Seufert (2009) PDX1 is involved in KLF11-induced inhibition of the human insulin promoter in rodent beta-cells. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0029-1221872
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