CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Stable overexpression of p8 increases survival of INS-1E beta cells in response to streptozotocin (STZ)-induced beta cell damage in vitro
DOI 10.1055/s-0029-1221873
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Autor:innenG Päth, E Tsaroucha, N Perakakis, I Pilz, M Alt, S Ehler, S van Loosen, J Seufert
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Within the pancreas, p8 expression is induced by pancreatitis and protects exocrine tissue from inflammatory damage. In previous work, we investigated the role of p8 within the endocrine pancreas and characterised p8 as a glucose-dependent mediator of beta cell proliferation. Here we investigate the cell protective properties of p8 in response to STZ treatment in INS-1E beta cells. Exposure of native INS-1E to STZ d…
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Zitierempfehlung
G Päth, E Tsaroucha, N Perakakis, I Pilz, M Alt, S Ehler, S van Loosen, J Seufert (2009) Stable overexpression of p8 increases survival of INS-1E beta cells in response to streptozotocin (STZ)-induced beta cell damage in vitro. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0029-1221873
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