CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
The metabolic regulator FGF-21 is induced by free fatty acids but not by PPARχ stimulation in man: Results of two randomized, controlled trials
DOI 10.1055/s-0029-1221953
Bibliografische Angaben
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Autor:innenK Mai, J Andres, J Weicht, S Meinus, T Bobbert, F Reinecke, M Möhlig, M Weickert, A Pfeiffer, J Spranger
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Objective: Fibroblast growth factor 21 (FGF-21) improves insulin sensitivity and lipid metabolism in obese or diabetic animal models, while human studies revealed increased FGF-21 levels in obesity and type 2 diabetes. Given that FGF-21 has been suggested to be a PPARα-dependent regulator of fasting metabolism, we hypothesized that free fatty acids, natural agonists of PPARα, might modify FGF-21 levels. Furthermore…
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Zitierempfehlung
K Mai, J Andres, J Weicht, S Meinus, T Bobbert, F Reinecke, M Möhlig, M Weickert, A Pfeiffer, J Spranger (2009) The metabolic regulator FGF-21 is induced by free fatty acids but not by PPARχ stimulation in man: Results of two randomized, controlled trials. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0029-1221953
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