CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Activated protein C signaling via protease activated receptor-3 protects against glucose induced podocyte apoptosis
DOI 10.1055/s-0029-1221985
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Thati, H Wang, I Vinnikov, M Kashif, K Shahzad, V Schwenger, PP Nawroth, B Isermann
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Activated protein C (APC) exerts anti-coagulant, anti-inflammatory and anti-apoptotic activities. We have recently shown that APC modulates diabetic nephropathy by inhibiting endothelial and podocyte apoptosis. The cyto-protective effects of APC on endothelial cells require endothelial protein C receptor (EPCR) and protease activated receptor-1 (PAR-1). However, it is not known how APC regulates podocyte function. E…
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Zitierempfehlung
M Thati, H Wang, I Vinnikov, M Kashif, K Shahzad, V Schwenger, PP Nawroth, B Isermann (2009) Activated protein C signaling via protease activated receptor-3 protects against glucose induced podocyte apoptosis. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0029-1221985
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