CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
CYP24A1 polymorphisms and its influence on 25(OH)D3 and 1,25(OH)2D3 serum levels in German type 1 diabetes patients
DOI 10.1055/s-0029-1222086
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Nachweis in CareLit
Autor:innenC Greissl, M Penna-Martinez, K Badenhoop, E Ramos-Lopez
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: The vitamin D system has been implicated in type 1 diabetes (T1D) by epidemiological and immune intervention studies as well as by polymorphisms of the vitamin D binding protein (DBP) and CYP27B1 genes. The 25(OH)D3–24-hydroxylase (CYP24), a cytochrome P450 enzyme, initiates the inactivation or catabolism of the vitamin D metabolites. Thus, CYP24 hydroxyls 1,25(OH)2D3 to the less active from 1,24,25(OH)2…
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Zitierempfehlung
C Greissl, M Penna-Martinez, K Badenhoop, E Ramos-Lopez (2009) CYP24A1 polymorphisms and its influence on 25(OH)D3 and 1,25(OH)2D3 serum levels in German type 1 diabetes patients. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0029-1222086
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