CareLit · DOI-Nachweis · Klinische Pädiatrie
Epigenetic inactivation of HHIP in brain tumors
DOI 10.1055/s-0029-1222623
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Angerer, A von dem Knesebeck, A Koch, A Waha, J Felsberg, J Hammes, T Pietsch, A Waha
ZeitschriftKlinische Pädiatrie
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The hedgehog signalling pathway is essential for cell proliferation, differentiation and tissue patterning during embryogenesis and remains active also in some adult tissues. An uncontrolled activation of this pathway, however, can lead to tumor development. There is firm evidence that unregulated hedgehog signalling plays a role in medulloblastomas and gliomas. Loss of heterozygosity of the PATCHED locus (PTCH), wh…
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Zitierempfehlung
A Angerer, A von dem Knesebeck, A Koch, A Waha, J Felsberg, J Hammes, T Pietsch, A Waha (2009) Epigenetic inactivation of HHIP in brain tumors. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0029-1222623
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