CareLit · DOI-Nachweis · Klinische Pädiatrie
Functional characterization of novel BRAF fusion gene in pilocytic astrocytomas
DOI 10.1055/s-0029-1222629
Bibliografische Angaben
Nachweis in CareLit
Autor:innenH Cin, M Remke, D Sturm, H Witt, S Wolf, A Korshunov, P Lichter, A Kulozik, S Pfister
ZeitschriftKlinische Pädiatrie
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Pilocytic astrocytomas (PA) constitute the most common brain tumors in children. Little is known about the molecular mechanisms contributing to the development of PA. Recently, we have identified duplications at chromosome 7q34 harboring the BRAF locus in 53% (28/53) of PA. Jones and colleagues could show that this tandem duplication results in a novel fusion gene between KIAA1549 and BRAF (Cancer Res 2008). Notably…
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Zitierempfehlung
H Cin, M Remke, D Sturm, H Witt, S Wolf, A Korshunov, P Lichter, A Kulozik, S Pfister (2009) Functional characterization of novel BRAF fusion gene in pilocytic astrocytomas. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0029-1222629
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