CareLit · DOI-Nachweis · Klinische Pädiatrie
Displacement of wild type lymphopoiesis by bone marrow cells lacking the BH3-only proteins BIM or BMF but not puma
DOI 10.1055/s-0029-1222633
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Erlacher, V Labi, D Bertele, N Fischer, CM Niemeyer, A Villunger
ZeitschriftKlinische Pädiatrie
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Apoptosis plays an important physiological role in the regulation of haematopoietic stem cell (HSC) homeostasis. In contrast, unwanted death of HSC during bone marrow transplantation compromises the efficacy of stem cell therapy. We aim to identify the pathways leading to HSC apoptosis following to different cellular stresses. We focus on the so called BH3-only proteins (i.e. Bim, Puma and Bmf), which are pro-apopto…
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Zitierempfehlung
M Erlacher, V Labi, D Bertele, N Fischer, CM Niemeyer, A Villunger (2009) Displacement of wild type lymphopoiesis by bone marrow cells lacking the BH3-only proteins BIM or BMF but not puma. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0029-1222633
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