CareLit · DOI-Nachweis · Klinische Pädiatrie
MicroRNAs contribute to the leukemogenic effect of MLL-AF9
DOI 10.1055/s-0029-1222635
Bibliografische Angaben
Nachweis in CareLit
Autor:innenKK Fleischmann, J von Frowein, T Magg, P Pagel, M Albert, I Schmid, AA Roscher
ZeitschriftKlinische Pädiatrie
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: The translocation t(9;11) (p22;q23) is frequent in acute myeloid leukemia (AML M5). It leads to the expression of the fusion-gene and -protein MLL-AF9, which has a proven leukemogenic effect whereas it's mechanism of leukemogenesis is largely unknown. MicroRNAs (miRNAs) are potent regulators of gene expression and are widely involved in the development of cancer. We hypothesized that at least part of the leuke…
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Zitierempfehlung
KK Fleischmann, J von Frowein, T Magg, P Pagel, M Albert, I Schmid, AA Roscher (2009) MicroRNAs contribute to the leukemogenic effect of MLL-AF9. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0029-1222635
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