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Histone deacetylases 5 and 9 are novel markers for medulloblastoma risk stratification and potential drug targets for therapy

T Milde, I Oehme, S Pfister, A Korshunov, A Kopp-Schneider, M Remke, H Deubzer, M Lodrini, A von Deimling, O Witt · Klinische Pädiatrie · Ausgabe 05/2009

DOI 10.1055/s-0029-1222661

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Autor:innenT Milde, I Oehme, S Pfister, A Korshunov, A Kopp-Schneider, M Remke, H Deubzer, M Lodrini, A von Deimling, O Witt
ZeitschriftKlinische Pädiatrie
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Medulloblastomas are the most common malignant brain tumors in childhood and 5-year survival rates of large-cell/anaplastic medulloblastoma or metastasized disease are as low as 30–40%. Furthermore, surviving children suffer from high morbidity due to therapy-related side effects. Thus, therapies targeting tumors in a specific manner, as opposed to the current surgery/irradiation/chemotherapy protocols, are urgently…

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Zitierempfehlung

T Milde, I Oehme, S Pfister, A Korshunov, A Kopp-Schneider, M Remke, H Deubzer, M Lodrini, A von Deimling, O Witt (2009) Histone deacetylases 5 and 9 are novel markers for medulloblastoma risk stratification and potential drug targets for therapy. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0029-1222661

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