CareLit · DOI-Nachweis · Klinische Pädiatrie
Transcription factor AP2alpha (TFAP2a) regulates differentiation and proliferation of neuroblastoma cells
DOI 10.1055/s-0029-1222666
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Autor:innenF Pentek, J Kirfel, S Lim, A Schramm, N Friedrichs, HE Deubzer, O Witt, R Buettner, A Eggert, JH Schulte
ZeitschriftKlinische Pädiatrie
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Neuroblastoma, the most common extracranial solid tumour of childhood, is derived from neural crest progenitor cells. The TFAP2a transcription factor regulates neural crest patterning. We sought to analyse TFAP2a expression in 97 primary neuroblastic tumors using a tissue microarray. TFAP2a was strongly expressed in poorly differentiated neuroblastomas, while TFAP2a expression was absent in tumor cells of differenti…
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Zitierempfehlung
F Pentek, J Kirfel, S Lim, A Schramm, N Friedrichs, HE Deubzer, O Witt, R Buettner, A Eggert, JH Schulte (2009) Transcription factor AP2alpha (TFAP2a) regulates differentiation and proliferation of neuroblastoma cells. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0029-1222666
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