CareLit · DOI-Nachweis · Klinische Pädiatrie
Characterization of HLA-A*0201 restricted cytotoxic CD8+ T cells directed against ewing tumor specific antigens
DOI 10.1055/s-0029-1222667
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Pirson, U Thiel, H Bernhard, GHS Richter, S Burdach
ZeitschriftKlinische Pädiatrie
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The rationale of adoptive T cell therapy is based on the attempt to circumvent pre-existing tolerance mechanisms by stimulating potentially tumor-reactive T cells ex vivo. Efforts to eradicate cancer by adoptive T cell transfer have been limited due to the difficulty of isolating tumor-reactive T cells present in low numbers in peripheral blood of tumor patients. Furthermore, the development of an effective immunoth…
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Zitierempfehlung
S Pirson, U Thiel, H Bernhard, GHS Richter, S Burdach (2009) Characterization of HLA-A*0201 restricted cytotoxic CD8+ T cells directed against ewing tumor specific antigens. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0029-1222667
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