CareLit · DOI-Nachweis · Klinische Pädiatrie
Apoptosis deficiency defines prognostic subgroups and therapy resistance in a xenograft model of pediatric BCP-ALL
DOI 10.1055/s-0029-1222672
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Queudeville, SM Eckhoff, KM Debatin, LH Meyer
ZeitschriftKlinische Pädiatrie
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
We previously demonstrated that intact cytochrome c related activation of caspases in pediatric acute leukemia is only found in patients with favorable outcome. In a NOD/SCID/huALL model rapid engraftment (short time to leukemia, TTLshort) determines poor patient outcome. In xenograft leukemia samples intact apoptosis signaling was only found in the TTLlong group, whereas it was absent in TTLshort. In addition, a si…
Zitieren
Zitierempfehlung
M Queudeville, SM Eckhoff, KM Debatin, LH Meyer (2009) Apoptosis deficiency defines prognostic subgroups and therapy resistance in a xenograft model of pediatric BCP-ALL. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0029-1222672
Mit CareLit weiterarbeiten