CareLit · DOI-Nachweis · Klinische Pädiatrie
Prognostic role and functional analyses of miRNA expression in neuroblastoma
DOI 10.1055/s-0029-1222678
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Schlierf, P Mestdagh, T Thor, K DePreter, M Baumann, A Eggert, J Vandesompele, A Schramm, JH Schulte
ZeitschriftKlinische Pädiatrie
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
MicroRNAs (miRNA) are a recently discovered class of short RNAs that repress translation and promote mRNA degradation by sequence-specific interaction with mRNA. Deregulation of miRNAs has been observed in various malignancies. We here analysed the expression of 430 miRNAs in 62 neuroblastomas using high-throughput real-time PCR. We identified miRNA profiles correlating with survival, MYCN amplification or chromosom…
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Zitierempfehlung
S Schlierf, P Mestdagh, T Thor, K DePreter, M Baumann, A Eggert, J Vandesompele, A Schramm, JH Schulte (2009) Prognostic role and functional analyses of miRNA expression in neuroblastoma. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0029-1222678
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