CareLit · DOI-Nachweis · Klinische Pädiatrie
Lysine-Specific Demethylase 1 Is Strongly Expressed in Poorly Differentiated Neuroblastoma: Implications for Therapy
DOI 10.1055/s-0029-1222681
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJH Schulte, A Schramm, T Thor, S Lim, K Pajtler, S Kuhfittig-Kulle, E Metzger, R Schuele, R Buettner, J Kirfel, A and Eggert
ZeitschriftKlinische Pädiatrie
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aberrant epigenetic changes are hallmarks of most cancers. Recently, a new class of histone modifying enzymes, demethylases, was identified catalyzing the removal of methyl groups from histone H3 lysine residues. Here, we address the functional significance of lysine-specific demethylase 1 (LSD1) in neuroblastoma. LSD1 expression correlated with adverse outcome and was inversely correlated with differentiation in ne…
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Zitierempfehlung
JH Schulte, A Schramm, T Thor, S Lim, K Pajtler, S Kuhfittig-Kulle, E Metzger, R Schuele, R Buettner, J Kirfel, A and Eggert (2009) Lysine-Specific Demethylase 1 Is Strongly Expressed in Poorly Differentiated Neuroblastoma: Implications for Therapy. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0029-1222681
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