CareLit · DOI-Nachweis · Klinische Pädiatrie
Establishment of a clinically applicable human tyrosine hdroxylase DNA vaccine for anti-neuroblastoma immunotherapie
DOI 10.1055/s-0029-1222683
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Shibina, A Stermann, D Seidel, G Gaedicke, HN Lode, N Huebener
ZeitschriftKlinische Pädiatrie
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
DNA vaccination against cancer antigens often induces weak anti-tumor immune responses in humans. In order to enhance the effect, xenogeneic immunization is a promising approach, in particular for neuroblastoma (NB), the most common extracranial solid tumor in childhood. NB cells highly express the enzyme tyrosine hydroxylase (TH). A human TH (hTH) DNA vaccine has already been investigated in a syngeneic NB mouse mo…
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Zitierempfehlung
A Shibina, A Stermann, D Seidel, G Gaedicke, HN Lode, N Huebener (2009) Establishment of a clinically applicable human tyrosine hdroxylase DNA vaccine for anti-neuroblastoma immunotherapie. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0029-1222683
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