CareLit · DOI-Nachweis · Klinische Pädiatrie
NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD+-sirtuin-1-dependent pathway.
DOI 10.1055/s-0029-1222684
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Skokowa, D Lan, BK Thakur, K Gupta, G Cario, AM Brechlin, M Stanulla, K Welte
ZeitschriftKlinische Pädiatrie
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
We identified nicotinamide phosphoribosyltransferase (NAMPT), also known as pre-B cell colony enhancing factor (PBEF), as an essential enzyme mediating granulocyte colony-stimulating factor (G-CSF)-triggered granulopoiesis in healthy individuals and in individuals with severe congenital neutropenia (Skokowa J., et al. Nat Med. 2009;15(2):151–8). Intracellular NAMPT and NAD+ amounts in myeloid cells, as well as plasm…
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Zitierempfehlung
J Skokowa, D Lan, BK Thakur, K Gupta, G Cario, AM Brechlin, M Stanulla, K Welte (2009) NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD+-sirtuin-1-dependent pathway. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0029-1222684
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