CareLit · DOI-Nachweis · Klinische Pädiatrie
Gene expression profiling leads to new potential therapeutic targets for pediatric acute lymphoblastic leukemia
DOI 10.1055/s-0029-1222689
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Stursberg, M Queudeville, SM Eckhoff, KM Debatin, LH Meyer
ZeitschriftKlinische Pädiatrie
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
We transplanted primary leukemia samples into NOD/SCID mice and demonstrated inferior survival for patients whose cells led to manifestation of disease within 10 weeks (time to leukemia short/TTLshort) in contrast to patient samples with prolonged in vivo growth (TTLlong). TTL phenotypes can be distinguished by a gene expression signature, which identified 2 genes with prognostic impact in an independent patient coh…
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Zitierempfehlung
J Stursberg, M Queudeville, SM Eckhoff, KM Debatin, LH Meyer (2009) Gene expression profiling leads to new potential therapeutic targets for pediatric acute lymphoblastic leukemia. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0029-1222689
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