CareLit · DOI-Nachweis · Klinische Pädiatrie
Tyrosine phosphatase SHP-2 modulates the cell cycle regulator p27Kip1 in promyelocytic leukemia cells
DOI 10.1055/s-0029-1222692
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Nachweis in CareLit
Autor:innenI Tossidou, M Dangers, DT Brandt, A Koch, C Kardinal
ZeitschriftKlinische Pädiatrie
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Protein tyrosine phosphorylation controls a wide range of critical biological processes. Recently, we provided the first evidence that the level of tyrosine phosphorylation of the cell cycle regulator p27Kip1 plays a crucial role in its binding to cyclin dependent kinases and its subcellular localization. While Src and Bcr-Abl were shown to be responsible for tyrosine phosphorylation, no data are available on the de…
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Zitierempfehlung
I Tossidou, M Dangers, DT Brandt, A Koch, C Kardinal (2009) Tyrosine phosphatase SHP-2 modulates the cell cycle regulator p27Kip1 in promyelocytic leukemia cells. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0029-1222692
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