CareLit · DOI-Nachweis · Klinische Pädiatrie
Oncogene c-MYC inhibition prevents cell growth and decreases sensitivity to radio- and chemotherapy in childhood medulloblastoma cells
DOI 10.1055/s-0029-1222695
Bibliografische Angaben
Nachweis in CareLit
Autor:innenAO von Bueren, T Shalaby, C Oehler-Jänne, M Pruschy, S Rutkowski, MA Grotzer
ZeitschriftKlinische Pädiatrie
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Recently, we demonstrated again the negative prognostic relevance of high c-MYC expression in childhood medulloblastoma (MB) in the prospective multicenter trial HIT'91. However, the mechanism by which c-MYC is associated with poor prognosis is not known in MB. We down-regulated c-MYC expression by using small interfering RNA (siRNA) and investigated changes in cellular proliferation, cell cycle analysis, apoptosis,…
Zitieren
Zitierempfehlung
AO von Bueren, T Shalaby, C Oehler-Jänne, M Pruschy, S Rutkowski, MA Grotzer (2009) Oncogene c-MYC inhibition prevents cell growth and decreases sensitivity to radio- and chemotherapy in childhood medulloblastoma cells. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0029-1222695
Mit CareLit weiterarbeiten