CareLit · DOI-Nachweis · Klinische Pädiatrie
RANK (TNFRSF11A) is epigenetically altered and inactivated in human gliomas
DOI 10.1055/s-0029-1222696
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Autor:innenA von dem Knesebeck, J Felsberg, T Mikeska, W Hartmann, A Waha, E Endl, J Hammes, T Pietsch, A Waha
ZeitschriftKlinische Pädiatrie
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Alterations of DNA methylation play an important role in carcinogenesis and influence the transcription of tumor suppressor genes in many tumor entities. Using a microarray based technology, we have identified novel candidate genes, which are de novo methylated in gliomas. One of these candidate genes is TNFRSF11A, also known as Receptor Activator of NF-κB (RANK), which after binding of the ligand RANKL activates se…
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Zitierempfehlung
A von dem Knesebeck, J Felsberg, T Mikeska, W Hartmann, A Waha, E Endl, J Hammes, T Pietsch, A Waha (2009) RANK (TNFRSF11A) is epigenetically altered and inactivated in human gliomas. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0029-1222696
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