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Mesenchymal stromal cells: 1. in vitro expansion with platelet lysate, 2. in vivo administration for acute renal failure: Recovery through paracrine mechanism.

AR Zander, C Lange, C Westenfelder · Klinische Pädiatrie · Ausgabe 05/2009

DOI 10.1055/s-0029-1222699

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Autor:innenAR Zander, C Lange, C Westenfelder
ZeitschriftKlinische Pädiatrie
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Human bone marrow mesenchymal stromal cells (hMSC) are currently investigated for a variety of therapeutic applications. However, most expansion protocols still use fetal calf serum (FCS) as growth factor supplement which is a potential source of undesired xenogeneic pathogens. We established an expansion protocol for hMSC based on GMP-produced medium supplemented with platelet lysate (PL) obtained from human thromb…

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AR Zander, C Lange, C Westenfelder (2009) Mesenchymal stromal cells: 1. in vitro expansion with platelet lysate, 2. in vivo administration for acute renal failure: Recovery through paracrine mechanism. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0029-1222699

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