CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Correlation of primary kinase genotype and clinical outcome of Imatinib and Sunitinib for treatment of advanced GIST
DOI 10.1055/s-0029-1224080
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Nachweis in CareLit
Autor:innenK Tamas, Z Sapi, T Fule, G Bodoky
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2009
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background/Purpose: Most gastrointestinal stromal tumours (GISTs) harbour mutant KIT kinase, which is imatinib target. Sunitinib, which targets KIT and several other kinases, has demonstrated efficacy in patients with GIST after they experience imatinib failure. But not all patients benefit equally. We examined the impact of primary kinase genotype on imatinib and sunitinib activity. Patients/Methods: Tumour respons…
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Zitierempfehlung
K Tamas, Z Sapi, T Fule, G Bodoky (2009) Correlation of primary kinase genotype and clinical outcome of Imatinib and Sunitinib for treatment of advanced GIST. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0029-1224080
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