CareLit · DOI-Nachweis · Aktuelle Neurologie
T-cell intrinsic Smad7 determines Th1/Th17 differentiation and susceptibility to autoimmune encephalomyelitis
DOI 10.1055/s-0029-1238410
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Nachweis in CareLit
Autor:innenI Kleiter, J Song, D Lukas, M Hasan, A Croxford, C Becker, M Neurath, U Bogdahn, A Steinbrecher, A Waisman
ZeitschriftAktuelle Neurologie
Ausgabe10/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: T cells play an important role in the pathogenesis of multiple sclerosis and its model disease experimental autoimmune encephalomyelitis (EAE). The transforming growth factor (TGF)-β is a cytokine of great importance for T cell differentiation, proliferation and survival. While blocking T helper (Th)1 and Th2 differentiation, TGF-β is crucial for the generation of T regulatory (Treg) and Th17 cells. Obje…
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Zitierempfehlung
I Kleiter, J Song, D Lukas, M Hasan, A Croxford, C Becker, M Neurath, U Bogdahn, A Steinbrecher, A Waisman (2009) T-cell intrinsic Smad7 determines Th1/Th17 differentiation and susceptibility to autoimmune encephalomyelitis. Aktuelle Neurologie (10). https://doi.org/10.1055/s-0029-1238410
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