CareLit · DOI-Nachweis · Aktuelle Neurologie
Blockade of kinin receptor B1 but not B2 protects from experimental cerebral ischaemia and brain edema
DOI 10.1055/s-0029-1238430
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Nachweis in CareLit
Autor:innenC Kleinschnitz, S Bräuninger, M Austinat, T Renné, G Stoll
ZeitschriftAktuelle Neurologie
Ausgabe10/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and Purpose: Brain edema is detrimental in ischemic stroke and its treatment options are limited. Kinins are proinflammatory peptides that are released during tissue injury. The effects of kinins are mediated by 2 different receptors (B1 and B2 receptor [B1R and B2R]) and comprise induction of edema formation and release of proinflammatory mediators. Methods: Focal cerebral ischemia was induced in B1R kno…
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Zitierempfehlung
C Kleinschnitz, S Bräuninger, M Austinat, T Renné, G Stoll (2009) Blockade of kinin receptor B1 but not B2 protects from experimental cerebral ischaemia and brain edema. Aktuelle Neurologie (10). https://doi.org/10.1055/s-0029-1238430
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