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Quantitative motor phenotype assessment in pre-manifest and symptomatic Huntington's disease: tongue force analysis differentiates between disease stages and provides high phenotype correlation. Cross sectional results from the TRACK-HD St…

M Say, N Bechtel, A Sturrock, S van den Bogaard, C Jauffret, S Bohlen, DR Langbehn, JA Mills, TP Archarya, H Johnson, B Borowsky, A Durr, BR Leavitt, RAC Roos, SJ Tabrizi, B Landwehrmeyer, R Reilmann · Aktuelle Neurologie · Ausgabe 10/2009

DOI 10.1055/s-0029-1238518

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Autor:innenM Say, N Bechtel, A Sturrock, S van den Bogaard, C Jauffret, S Bohlen, DR Langbehn, JA Mills, TP Archarya, H Johnson, B Borowsky, A Durr, BR Leavitt, RAC Roos, SJ Tabrizi, B Landwehrmeyer, R Reilmann
ZeitschriftAktuelle Neurologie
Ausgabe10/2009
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Abstract-Vorschau

Background: Assessment of motor phenotype and diagnosis of Huntington's Disease (HD) are based on the Unified Huntington's Disease Rating Scale-Total Motor Score (UHDRS-TMS), a categorical clinical scale. Therefore, results of clinical trials are limited by (1) subjective error, (2) sensitivity of the categorical scale, and (3) insensitivity in pre-manifest subjects. More objective and quantitative measures of motor…

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Zitierempfehlung

M Say, N Bechtel, A Sturrock, S van den Bogaard, C Jauffret, S Bohlen, DR Langbehn, JA Mills, TP Archarya, H Johnson, B Borowsky, A Durr, BR Leavitt, RAC Roos, SJ Tabrizi, B Landwehrmeyer, R Reilmann (2009) Quantitative motor phenotype assessment in pre-manifest and symptomatic Huntington's disease: tongue force analysis differentiates between disease stages and provides high phenotype correlation. Cross sectional results from the TRACK-HD Study. Aktuelle Neurologie (10). https://doi.org/10.1055/s-0029-1238518

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