CareLit · DOI-Nachweis · Aktuelle Neurologie
Evidence for a role of the Bcl-2 family in the pathophysiology of Parkin-associated parkinsonism using a human fibroblast model
DOI 10.1055/s-0029-1238561
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Autor:innenS Orolicki, A Grunewald, A Rakovic, P Seibler, K Lohmann, N Kock, C Klein
ZeitschriftAktuelle Neurologie
Ausgabe10/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Parkinson's disease (PD) is a primarily sporadically occurring neurodegenerative disorder of advanced age. In the last few years several genes have been identified, including Parkin, coding for an E3 ligase involved in proteasomal protein degradation. Recent findings implicate oxidative damage and apoptosis as key molecular mechanisms of both sporadic and familial PD. To characterize the possible role of molecular m…
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Zitierempfehlung
S Orolicki, A Grunewald, A Rakovic, P Seibler, K Lohmann, N Kock, C Klein (2009) Evidence for a role of the Bcl-2 family in the pathophysiology of Parkin-associated parkinsonism using a human fibroblast model. Aktuelle Neurologie (10). https://doi.org/10.1055/s-0029-1238561
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