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Genetic variants of folate and methionine metabolism and primary central nervous system lymphoma incidence in a German cohort of 185 patients

D Kurzwelly, S Knop, J Löffler, A Korfel, E Thiel, H Hebart, M Weller, M Linnebank, U Herrlinger · Aktuelle Neurologie · Ausgabe 10/2009

DOI 10.1055/s-0029-1238735

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Autor:innenD Kurzwelly, S Knop, J Löffler, A Korfel, E Thiel, H Hebart, M Weller, M Linnebank, U Herrlinger
ZeitschriftAktuelle Neurologie
Ausgabe10/2009
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Objective: Functional genetic polymorphisms of folate and methionine metabolism play an important role in DNA synthesis and methylation, and affect the risk of various cancers including lymphoproliferative disorders. In a retrospective analysis of 185 immunocompetent patients with primary central nervous system lymphoma (PCNSL) and 212 population controls we therefore investigated eight polymorphisms in folate-metab…

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Zitierempfehlung

D Kurzwelly, S Knop, J Löffler, A Korfel, E Thiel, H Hebart, M Weller, M Linnebank, U Herrlinger (2009) Genetic variants of folate and methionine metabolism and primary central nervous system lymphoma incidence in a German cohort of 185 patients. Aktuelle Neurologie (10). https://doi.org/10.1055/s-0029-1238735

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