CareLit · DOI-Nachweis · Aktuelle Neurologie
Inhibition of glioma cell growth in vitro and in vivo by a novel proteasome inhibitor
DOI 10.1055/s-0029-1238736
Bibliografische Angaben
Nachweis in CareLit
Autor:innenP Roth, M Kissel, C Herrmann, G Eisele, J Leban, M Weller, F Schmidt
ZeitschriftAktuelle Neurologie
Ausgabe10/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The prognosis of patients with malignant gliomas remains poor. Inhibition of the proteasome of glioma cells may provide a promising therapeutic strategy. Here, we describe the in vitro and in vivo effects of SC68896, a novel agent developed as an inhibitor of the proteasome. Application of SC68896 to cancer cells of different origin, including gliomas, inhibits their proliferation in vitro. Only nanomolar concentrat…
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Zitierempfehlung
P Roth, M Kissel, C Herrmann, G Eisele, J Leban, M Weller, F Schmidt (2009) Inhibition of glioma cell growth in vitro and in vivo by a novel proteasome inhibitor. Aktuelle Neurologie (10). https://doi.org/10.1055/s-0029-1238736
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