CareLit · DOI-Nachweis · Aktuelle Neurologie
Effect of natalizumab treatment on soluble adhesion molecules
DOI 10.1055/s-0029-1238768
Bibliografische Angaben
Nachweis in CareLit
Autor:innenK Oppermann, G Pilz, P Wipfler, C Sulzer, S Afazel, E Haschke-Becher, A Kunz, S Golaszewski, G Ladurner, J Kraus
ZeitschriftAktuelle Neurologie
Ausgabe10/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Natalizumab (Tysabri) is a monoclonal antibody used in the treatment of multiple sclerosis (MS). This humanized antibody binds directly at the α4-integrin subunit of the adhesion molecule (AM) very late activation antigen-4 (VLA-4) and thus leads to an inhibition of immune cell extravasation across the blood brain barrier. This consecutively results in a reduced inflammation of the central nervous syst…
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Zitierempfehlung
K Oppermann, G Pilz, P Wipfler, C Sulzer, S Afazel, E Haschke-Becher, A Kunz, S Golaszewski, G Ladurner, J Kraus (2009) Effect of natalizumab treatment on soluble adhesion molecules. Aktuelle Neurologie (10). https://doi.org/10.1055/s-0029-1238768
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