CareLit · DOI-Nachweis · Aktuelle Neurologie
Adhesion molecule expression indicates a therapeutical effect of natatizumab despite the presence of neutralizing antibodies
DOI 10.1055/s-0029-1238769
Bibliografische Angaben
Nachweis in CareLit
Autor:innenG Pilz, P Wipfler, K Oppermann, C Sulzer, A Kunz, S Golaszewski, S Afazel, E Haschke-Becher, G Ladurner, J Kraus
ZeitschriftAktuelle Neurologie
Ausgabe10/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Objective: We report on serial α4-integrin expression levels of a patient with neutralizing anti-Natalizumab-antibodies. Background: Natalizumab is a humanized monoclonal antibody directed against the adhesion molecule α4-integrin. Neutralizing anti-natalizumab-antibodies have been found to reduce the beneficial effects of Natalizumab treatment in multiple sclerosis (MS). Moreover, detection of high-titred neutraliz…
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Zitierempfehlung
G Pilz, P Wipfler, K Oppermann, C Sulzer, A Kunz, S Golaszewski, S Afazel, E Haschke-Becher, G Ladurner, J Kraus (2009) Adhesion molecule expression indicates a therapeutical effect of natatizumab despite the presence of neutralizing antibodies. Aktuelle Neurologie (10). https://doi.org/10.1055/s-0029-1238769
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