CareLit · DOI-Nachweis · Aktuelle Neurologie
Integrative modelling of transcriptional regulation in response to interferon β multiple sclerosis treatment
DOI 10.1055/s-0029-1238773
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Autor:innenM Hecker, RH Goertsches, D Koczan, HJ Thiesen, R Guthke, UK Zettl
ZeitschriftAktuelle Neurologie
Ausgabe10/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The purpose of this study was to characterize the transcriptional effects induced by an interferon-β-1a (IFN-b) treatment regime (Avonex; weekly 30 mcg intramuscular) in patients with relapsing-remitting form of multiple sclerosis (MS). IFN-b effectively decreases the frequency of clinical exacerbations in most MS patients, but the specifically modulated genes and mechanisms by which IFN-b exerts its effects have no…
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Zitierempfehlung
M Hecker, RH Goertsches, D Koczan, HJ Thiesen, R Guthke, UK Zettl (2009) Integrative modelling of transcriptional regulation in response to interferon β multiple sclerosis treatment. Aktuelle Neurologie (10). https://doi.org/10.1055/s-0029-1238773
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