CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Maintained IL-18bp secretion by intestinal epithelial cells upon selective inhibition of IFN-γ-dependent apoptosis
DOI 10.1055/s-0029-1241297
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Autor:innenD Schuhmann, P Godoy, MV Singer, S Dooley, U Böcker
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Interferon (IFN)-γ is capable of inducing apoptosis in intestinal epithelial cells (IEC), even in absence of other pro-apoptotic stimuli. At the same it alters the interleukin (IL)-18/IL-18 binding protein (bp) ratio in vitro as well as in vivo. Aim: To study presence of IL-18bp in vivo and to inhibit IFN-γ mediated apoptosis, while preserving IFN-γ dependent up-regulation of IL-18bp in vitro. Methods:…
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Zitierempfehlung
D Schuhmann, P Godoy, MV Singer, S Dooley, U Böcker (2009) Maintained IL-18bp secretion by intestinal epithelial cells upon selective inhibition of IFN-γ-dependent apoptosis. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0029-1241297
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