CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
IL-27 increases intestinal epithelial cell proliferation and migration and its mRNA expression is up-regulated in active Crohn's disease
DOI 10.1055/s-0029-1241329
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Nachweis in CareLit
Autor:innenT Olszak, J Diegelmann, E de Toni, B Göke, S Brand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2009
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background & aims: Interleukin (IL)-27, a member of the IL-6/IL-12 cytokine family, is a heterodimeric cytokine composed of EBI3 and p28 which signals via the heterodimeric IL-27R (WSX-1)/gp130 receptor complex. IL-27 is closely related to IL-12 and IL-23. Given that gp130 expression has been shown in intestinal epithelial cells (IECs), we here analyzed whether IL-27R is also expressed in this cell type. Moreover, w…
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Zitierempfehlung
T Olszak, J Diegelmann, E de Toni, B Göke, S Brand (2009) IL-27 increases intestinal epithelial cell proliferation and migration and its mRNA expression is up-regulated in active Crohn's disease. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0029-1241329
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