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Colorectal cancer-derived intestinal epithelial cells express the functional receptor complex for IL-17F mediating MAP kinase activation and wound healing

T Olszak, J Diegelmann, E de Toni, B Göke, S Brand · Zeitschrift für Gastroenterologie · Ausgabe 09/2009

DOI 10.1055/s-0029-1241331

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Autor:innenT Olszak, J Diegelmann, E de Toni, B Göke, S Brand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe09/2009
Jahrgang / SeitenNicht angegeben

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Background & aims: Interleukin (IL)-17F is a novel proinflammatory cytokine which is a member of the IL-17 cytokine family. IL-17F mediates signal transduction via the heterodimeric IL-17RA/IL-17RC receptor complex. IL-17F is closely related to IL-17A. Both cytokines are secreted by Th17 cells which play a major role in the pathogenesis of Crohn's disease (CD) and other autoimmune diseases. Previous studies demonstr…

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Zitierempfehlung

T Olszak, J Diegelmann, E de Toni, B Göke, S Brand (2009) Colorectal cancer-derived intestinal epithelial cells express the functional receptor complex for IL-17F mediating MAP kinase activation and wound healing. Zeitschrift für Gastroenterologie (09). https://doi.org/10.1055/s-0029-1241331

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